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教师名录

张茜茜
教授(特聘)

办公地点:化生学院

办公电话:

电子邮件:zhangqianqian186@hotmail.com

本科课程:《基因组学》 (本研通选)、《数量遗传与基因组学》、《数据科学:R语言基础》、《基因组计划与高通量测序》

研究生课程:

科研方向:统计数量遗传学、进化及群体遗传学、动植物遗传育种、化学遗传学等

社会职务:北京市女科协理事

简    历

2007-2011 西北农林科技大学 本科

2011-2013 奥地利维也纳自然资源与生命科学大学 硕士

2011-2013 荷兰瓦赫宁根大学 硕士

2013-2016 丹麦奥胡斯大学 博士

2013-2017 荷兰瓦赫宁根大学 博士

2018-2019 丹麦哥本哈根大学 博士后

2018-2020 丹麦奥胡斯大学 博士后/客座研究员

2020-至今 丹麦奥胡斯大学 客座研究员

2023-至今 北京科技大学 教授(特聘)

科研业绩

主持或参与项目课题:

国家自然科学基金青年项目、北京市科技新星计划、外国专家交流合作项目、高层次海外留学归国人才计划、人类UKBB精准医疗算法开发项目、国际1000头公牛基因组计划、丹麦动植物基因组选择育种项目、荷兰Breed4Food项目;欧盟Erasmus Mundus全额奖学金计划(硕士、博士项目)等

招生计划

每年招收硕士生2名、博士生1名

代表性论文著作

1. X. Xie, X. Jiao, K. Yang, Q. Zhang*. A case study of comprehensive Association Analysis and Risk Prediction of Amyotrophic Lateral Sclerosis in a Chinese Population. Molecular Biology Reports. (2026). Accepted.

2. Q. Zhang*, B. Cui, X. Dong, W. Lv, X. Xie, Y. Wang, Z. Guo, and J. Jensen. "Mapping of identity by descent reveals genes shaping morphology and biological traits in the cultivated lettuce varieties during the long-term crossbreeding." Theoretical and Applied Genetics 138, 5 (2025): 99.

3. Q. Zhang*, W. Lv, D. Liu, X. Xie, K. Yang, Y. Tang, and J. Solkner. "Distribution of runs of homozygosity in Lactuca species and its implications for plant breeding and evolutionary conservation." BMC genomics 26, 1 (2025): 481.

4. Q. Zhang*, L. Ding*, X. Xie, L. Ru, Q. Li, C. Yao, J. Solkner J and R.  Jiang. Third-generation sequencing reveals the spatial variation of microbial composition of airborne bacteria in an intensive dairy farm. Frontiers in Microbiology (2025): 16:1688472. doi: 10.3389/fmicb.2025.1688472.

5. B. Cui; Z. Guo; H. Cao; M. Calus; Q. Zhang*, The computational implementation of a platform of relative Identity by Descent scores algorithm for introgressive mapping. Frontiers in Genetics (2023): 3409.

6. Q. Zhang*; A. Amanda Schönherz; M. Sandø Lund; B. Guldbrandtsen, Positive Selection and Adaptive Introgression of Haplotypes from Bos indicus Improve the Modern Bos taurus Cattle., Agriculture (2022), 12:844, https://doi.org/10.3390/agriculture12060844.

7. Q. Zhang*; Q. Zhang; J. Jensen, Association studies and genomic prediction for genetic improvements in agriculture., Frontiers in Plant Science (2022), 13: 904230, DOI: 10.3389/fpls.2022.904230.

8. Q. Zhang, F. Privé, B. Vilhjálmsson, D. Speed*,Improved genetic prediction of complex traits from individual-level data or summary statistics, Nature Communications (2021), 12:4192.  

9. Q. Zhang#, Z. Cai#, M. Lhomme, G. Sahana, P. Lesnik, M. Guerin, M. Fredhold, P. Karlskov-Mortensen. Inclusion of endophenotypes in a standard GWAS facilitate a detailed mechanistic understanding of genetic elements that control blood lipid levels. Scientific Reports, (2020), 10:18434.

10. Q. Zhang*, G. Difford, G. Sahana, P. Løvendahl, J. Lassen, M. Lund, B. Guldbrandtsen, L. Janss. Bayesian modelling reveals host genes associated with rumen microbiomes jointly influencing methane emission in cattle. The ISME Journal (2020), DOI: https://doi.org/10.1038/s41396-020-0663-x.

11. Q. Zhang*, M. Calus, M. Bosse, G. Sahana, M. Lund, B. Guldbrandtsen. Human-Mediated Introgression of Haplotypes in a Modern Dairy Cattle Breed. Genetics (2018), DOI: https://doi.org/10.1534/genetics.118.301143. (selected as highlights)

12. Q. Zhang*, M. Calus, B. Guldbrandtsen, M. Lund, G. Sahana. Contribution of rare and low-frequency whole-genome sequence variants to complex traits variation in dairy cattle. Genetics Selection Evolution (2017), 49(1):60. 

13. Q. Zhang*, B. Guldbrandtsen, J. Thomasen, M. Lund, G. Sahana. Genome-wide association study for longevity with whole genome sequence in three cattle breeds. Journal of Dairy Science (2016), DOI: http://dx.doi.org/10.3168/jds.2015-10697.

14. Q. Zhang*, M. Calus, B. Guldbrandtsen, M. Lund, G. Sahana. Comparison of rare variant association mapping methods for quantitative traits in cattle population with complex familial relationship. Genetics Selection Evolution (2016), 48(1): 60.

15. Q. Zhang*, B. Guldbrandtsen, M. Bosse, M. Lund, G. Sahana*. Runs of homozygosity and distribution of functional variants in the cattle genome. B M C Genomics (2015), 16(1):542.

16. Q. Zhang*, M. Calus, B. Guldbrandtsen, M. Lund, G. Sahana*. Estimation of inbreeding using pedigree, 50k SNP chip genotypes and full sequence data in three cattle breeds. B M C Genetics (2015), 16(1):88.

17. Q. Zhang*, G. Sahana, B. Guldbrandtsen, M. Lund, M. Calus. Impact of rare and low-frequency sequence variants on accuracy of genomic prediction in dairy cattle. Genetics Selection Evolution (2018), 50:62. 

18. H. Wang, X. Wang, Q. Zhang, X. Miao, L. Chen, L. Sun, H. Shi. Global transcriptome characterization of peripheral blood mononuclear cells in individuals with chronic HIV infection. Genomics (2025), p.111082.

19. Y. Wang, R. Yao, L. Zhao, Q. Zhang, M. Li, X. Kong, P. Liu, S. Huang, C. Hu, Z. Bao, X. Hu. Optimizing Strategy for Whole-Genome Genotype Imputation in Scallops. Aquaculture (2025), Jan 30;595:741492.

20. Z. Zhang, Q. Xiao, Q. Zhang, H. Sun, J. Chen, Z. Li, M. Xue, P. Ma et al. Genomic analysis reveals genes affecting distinct phenotypes among different Chinese and western pig breeds. Scientific Reports (2018), 8(1): 13352.

21. Z. Zhang, Q. Zhang, Q. Xiao, H. Sun, Y. Yang, J. Chen, Z. Li, M. Xue, P. Ma et al. The distribution of runs of homozygosity in Chinese and western pig breeds evaluated by reduced-representation sequencing data. Animal Genetics (2018), DOI: https://doi.org/10.1111/age.12730.

22. X. Jing, L. Zan, J. Huang, Q. Zhang, B. Li. Research and Implementation Based on B/S Model Selection of Beef Evaluation System, China Cattle Science (2011), 37(2):20-23.

23. T. Dekar, KT. Gebre, G. Mészáros, M. Derks, Q. Zhang, J. Himmelbauer, J. Sölkner. Detection of hemizygous deletions in the genome of Fleckvieh cattle using SNP chip data and the concept of Mendelian mismatches in parent-offspring pairs. Anim Genet. (2025), Dec;56(6):e70057. doi: 10.1111/age.70057. PMID: 41139989.

24. Q. Zhang, B. Guldbrandtsen, M. Lund, G. Sahana, M. Calus. Can rare variants improve the reliability of genomic prediction in dairy cattle? Abstract book of 4th Annual Danish Bioinformatics Conference (2018).

25. Q. Zhang, B. Guldbrandtsen, M. Lund, G. Sahana. Rare variants from imputed whole genome sequence explain a small fraction of the total genetic variance in different traits in cattle. Abstract book of 5th ICQG (2016).

26. Q. Zhang, B. Guldbrandtsen, M. Bosse, M. Lund, G. Sahana. Runs of homozygosity and distribution of functional variants in cattle genome. Proceedings in 10th WCGALP (2014).

27. Q. Zhang, B. Guldbrandtsen, M. Lund, G. Sahana. Inbreeding, admixture and selection signature in Danish Cattle breeds. Proceedings in 34th ISAG (2014).

28. S. Boitard, M. Dolezal, B. Servin, D. Fischer, J. Decker, I. Macleod, Q. Zhang, B. Guldbrandtsen, M. Lund, A. Bagnato, J. Vilkki and the 1000 bull genomes project. Disentangling demography and selection effects of cattle domestication - new insights from the 1000 bull genomes project. Abstract book of SMBE (2015).

29. A. Schönherz, Q. Zhang, V. Nielsen, B. Guldbrandtsen. Genetic Diversity and Population Structure of the Red Danish Dairy Cattle Breed. Abstract book of SMBE (2015).

研究生培养情况

已毕业本科生1名(成功考研至中科院过程所)